Features: S-Adenosylmethionine is an endogenous molecule synthesized by cells throughout the body. Formed from the amino acid methionine and ATP, S-Adenosylmethionine is an essential part of three major biochemical pathways: transmethylation, transsulfuration and aminopropylation. As part of these pathways, S-Adenosylmethionine is essential to all cells and is particularly important in hepatocytes because of their central role in metabolism. Deficiency of S-Adenosylmethionine has been associated with a spectrum of cellular derangements that have profound effects on hepatocytes, and in fact there is evidence that a deficiency of S-Adenosylmethionine in the body may initiate or contribute to abnormalities of cellular structure and function in many body tissues, including the liver.1-3 Conversely, exogenous administration of S-Adenosylmethionine has been shown to result in improvements in hepatocellular function in both in-vivo and in-vitro studies, without cytotoxicity or significant side effects.4-8 Precursors of S-Adenosylmethionine do not have similar effects. Administration of large amounts of methionine has no beneficial effect on S-Adenosylmethionine levels and may be toxic.9 The only way to increase S-Adenosylmethionine levels is by direct supplementation with S-Adenosylmethionine.
Benefits: Support Liver Function
Dosage: 10mg/kg BW BID,
(1 tab contains 100 mg S-Adenosyl-l-methionine)